Hotels in Wapello

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March 2025
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Where to stay in Wapello?

Columbus Motel
Free WiFi, bed sheets

Columbus Motel

2.5 star property
5.6 out of 10, (35)
The price is $75
includes taxes & fees
$72 per night
Jan 27 - Jan 28
Columbus Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Wapello

The region around Wapello is home to attractions such as Mississippi River and Cairo Woods Wildlife Area.

See all hotels in Wapello

Frequently asked questions

What hotels do travelers recommend in Wapello?
Guests like Iowa Cabin: Rustic+Cozy. Lake Odessa water-view. Hunt, kayak, fish or explore..
Can I book a refundable accommodation in Wapello?
If you want the flexibility to change your plans to Wapello, most properties offer refundable* rates you can book. You can see these properties by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Wapello be like during my trip?
July and August are typically the warmest months in Wapello when the average temp is 72°F. January and February are the coldest months when the average temperature is 30°F. June and May are the months with the most rain.
Why should I book my Wapello accommodation with Hotels.com?
There are lots of reasons to book your Wapello trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.