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Take your next trip up a notch in with a home away from home unlike any other. From city-center suites with iconic views to refurbished motels steeped in history, there are unique hotels to discover all over the US and beyond. Staying at a cool hotel doesn't just give you a correspondingly cool story to tell— it’s also a surefire way to experience your destination like a local and make unforgettable memories
Book Unique Hotel Stays in Popular Destinations
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Le Sorelle
3 reasons to book unique hotels on Hotels.com
Dig deeper into your destination
By booking a hotel that's linked to your location's unique features—be they its history, culture, or landscape—you'll have a richer experience.
Make unforgettable memories
Goodbye identikit chains, hello once-in-a-lifetime experiences. Staying in a unique hotel helps make your overall trip more unique, and more memorable, too.
Incredible photo opportunities
From historic features to stunning architecture, cool hotels often come with a raft of great photo spots—so you can relive your adventures anytime.
Book Unique Hotel Stays in Popular Destinations

New York Hotels
A hotel on Staten Island with views of the Statue of Liberty framed by Manhattan's skyscrapers? A cozy, all-wood lodge nestled in the heart of the Adirondacks, with nothing but trees as far as the eye can see? Or a sleek room with floor-to-ceiling windows overlooking Niagara Falls? The great state of New York is packed with diversity—and unique hotels to match. Whether you visit for a day, a week, or even longer, it's an excellent choice for one-of-a-kind stays.

Manhattan Hotels
Manhattan's iconic skyline is known the world over, with unmistakable structures like the Empire State Building shaping the city's image. Make the most of your time in this central borough with a unique hotel room that does justice to these sights: Pick your accommodations carefully and you might just be able to enjoy views of Central Park, the Chrysler Building, or the New York Public Library without even leaving your bed. It's worth spending at least a weekend in Manhattan to make the most of what's on offer and see the Big Apple's famous attractions.

California Hotels
As one of the country's largest states, it's no wonder that California is home to countless cool hotels. How about a luxury resortOpens in a new window in Joshua Tree, built from local materials and serving regional products? Or a refurbished 1960s motel on the edge of the former Route 66? And if you ever wanted to stay in a national park, Yosemite has a handful of lodging options that fit the bill. Stay for at least a few days to soak up the West Coast vibes and make the most of your unique hotel in California.

Chicago Hotels
The Windy City is known for its artistic flair—and what could be more unique than a hotel overlooking the mirrored Cloud Gate sculpture? And the cultural experience doesn't stop when you step inside your unique hotel in Chicago, either. From hotels with their own art collections displayed for the benefit of guests, to a property with its own 24/7 art museum, Chicago is packed with cool hotels for art lovers. It's worth spending at least 2 or 3 days in the city to make the most of its rich cultural landscape.

Ohio Hotels
As one of the US's major wine-growing regions, some of Ohio's most unique hotels are hidden away in wineries. What could be more memorable than sipping a glass or two made using grapes grown mere yards away from your bedroom, or waking up to the sight of hundreds upon hundreds of vines, stretching for miles? If you're planning to hop from one vineyard to the next, it's worth staying for at least 5 to 7 days so you can enjoy the area to the fullest and explore everything that these wineries have to offer.

Denver Hotels
In Denver, the past is truly present—home of the US Mint since 1863, this Old West destination is a prime pick for history buffs, that goes for its hotels, too. Take your tour of bygone days up a notch by staying in one-of-a-kind lodging in a historic building. From bed and breakfast accommodation in a Victorian mansion to a 5-star stay in a lavish renovated Art Deco landmark, there are countless unique hotels across Denver to discover. It's the ideal place for a weekend getaway to relax, unwind, and quench your thirst for discovering the past.
FAQ
What is the most unique hotel in the world?
From mountaintop resorts with one-of-a-kind views to beachfront lodging in hidden locations, the world's most unique hotels are endless and varied. Be it themed rooms, capsule accommodation, hidden wineries, or even treehouses, there are no limits to the creative options that you can find on Hotels.com




